Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 2/20 | 0.32 |
| ▸ | EDNRA | P25101 | 2/20 | 0.32 |
| ▸ | FURIN | P09958 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564981 | 1.00 | MAPK1 (0.34) | MAPK1CYP1A2MAPTADRA1ATP53 | |
| SCHEMBL9564975 | 1.00 | MAPK1 (0.34) | MAPK1CYP1A2MAPTADRA1ATP53 | |
| SCHEMBL9565062 | 0.91 | TP53 (0.34) | MAPK1MAPTADRA1ATP53FURIN | |
| SCHEMBL9565063 | 0.91 | TP53 (0.34) | MAPK1MAPTADRA1ATP53FURIN | |
| SCHEMBL9565065 | 0.91 | TP53 (0.34) | MAPK1MAPTADRA1ATP53FURIN | |
| SCHEMBL9565074 | 0.77 | ABCC9 (0.38) | AVPR1AGRM5 | |
| SCHEMBL9565076 | 0.77 | ABCC9 (0.38) | AVPR1AGRM5 | |
| SCHEMBL9565078 | 0.77 | ABCC9 (0.38) | AVPR1AGRM5 | |
| SCHEMBL8085199 | 0.74 | ABCC9 (0.42) | AVPR1ANPC1 | |
| SCHEMBL9565042 | 0.70 | LMNA (0.33) | MAPK1CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525768-A1 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1993-02-03 | — | — | EP | disclosed |