Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 11/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.32 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565076 | 1.00 | ABCC9 (0.38) | ABCC9GRM5HCRTR1HCRTR2ALK | |
| SCHEMBL9565078 | 1.00 | ABCC9 (0.38) | ABCC9GRM5HCRTR1HCRTR2ALK | |
| SCHEMBL9565062 | 0.84 | TP53 (0.34) | GRM5AVPR1A | |
| SCHEMBL9565063 | 0.84 | TP53 (0.34) | GRM5AVPR1A | |
| SCHEMBL9565065 | 0.84 | TP53 (0.34) | GRM5AVPR1A | |
| SCHEMBL9565067 | 0.81 | ABCC9 (0.34) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9565108 | 0.81 | ABCC9 (0.34) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9565070 | 0.81 | ABCC9 (0.34) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7274240 | 0.77 | ABCC9 (0.62) | ABCC9 | |
| SCHEMBL9733529 | 0.77 | ABCC9 (0.41) | ABCC9GRM5HCRTR1HCRTR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525768-A1 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1993-02-03 | — | — | EP | disclosed |