Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4265537 | 0.73 | HCAR2 (0.39) | LMNA | |
| SCHEMBL6543758 | 0.69 | ACHE (0.36) | LMNA | |
| SCHEMBL1899099 | 0.68 | KMT2A (0.49) | LMNA | |
| SCHEMBL27830052 | 0.67 | KMT2A (0.47) | LMNA | |
| Hydrochloric Acid SCHEMBL27648812 | 0.67 | KMT2A (0.47) | LMNA | |
| SCHEMBL9565016 | 0.65 | LMNA (0.39) | LMNA | |
| SCHEMBL28062249 | 0.65 | ALDH1A1 (0.32) | LMNA | |
| SCHEMBL27912644 | 0.65 | CTSL (0.33) | LMNA | |
| SCHEMBL27808820 | 0.65 | CDK2 (0.38) | LMNA | |
| SCHEMBL27752731 | 0.65 | CDK2 (0.38) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525768-A1 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1993-02-03 | — | — | EP | disclosed |