Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12391026 | 0.80 | CYP2D6 (0.42) | L3MBTL1TSHRALDH1A1LMNACYP1A2 | |
| SCHEMBL8880783 | 0.78 | TSHR (0.47) | L3MBTL1TSHRTDP1ALDH1A1ESR1 | |
| SCHEMBL7979485 | 0.77 | ELANE (0.49) | ELANEL3MBTL1TSHRTDP1ALDH1A1 | |
| SCHEMBL9565269 | 0.77 | MTNR1A (0.38) | L3MBTL1ALDH1A1LMNANPC1SMN1; SMN2 | |
| SCHEMBL6918344 | 0.75 | CYP3A4 (0.39) | TSHRLMNACYP1A2CYP2C19CYP2D6 | |
| SCHEMBL5132689 | 0.74 | MAPT (0.48) | ELANEL3MBTL1TSHRTDP1ALDH1A1 | |
| SCHEMBL16056651 | 0.71 | LMNA (0.51) | L3MBTL1TSHRTDP1ALDH1A1LMNA | |
| SCHEMBL14975448 | 0.71 | LMNA (0.51) | L3MBTL1TSHRTDP1ALDH1A1LMNA | |
| SCHEMBL14974933 | 0.71 | LMNA (0.51) | L3MBTL1TSHRTDP1ALDH1A1LMNA | |
| SCHEMBL9565270 | 0.71 | PLAAT3 (0.37) | L3MBTL1TDP1ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552760-A1 | Microbiological process for the preparation of 2-halopyrimidine-4-carboxylic acids | LONZA AG (CH) | 1993-07-28 | — | — | EP | disclosed |