Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.35 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.35 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.35 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196191 | 0.82 | MTNR1A (0.38) | MTNR1AMTNR1BALDH1A1KDM4EHPGD | |
| SCHEMBL27850219 | 0.81 | KDM4E (0.44) | MTNR1AMTNR1BTRPV1ALDH1A1PLAAT3 | |
| SCHEMBL9565278 | 0.79 | PLAAT3 (0.34) | TRPV1ALDH1A1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL9565270 | 0.79 | PLAAT3 (0.37) | TRPV1ALDH1A1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL15881243 | 0.78 | LMNA (0.35) | TRPV1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL25984978 | 0.77 | KDM4C (0.44) | ALDH1A1L3MBTL1AAK1SMN1; SMN2NPC1 | |
| SCHEMBL6643662 | 0.77 | MEN1 (0.46) | TRPV1ALDH1A1KDM4EL3MBTL1AAK1 | |
| SCHEMBL9565271 | 0.77 | ELANE (0.42) | ALDH1A1HPGDL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL9326030 | 0.75 | L3MBTL1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL6225917 | 0.75 | KDM4E (0.48) | MTNR1AMTNR1BALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552760-A1 | Microbiological process for the preparation of 2-halopyrimidine-4-carboxylic acids | LONZA AG (CH) | 1993-07-28 | — | — | EP | disclosed |