Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686891 | 0.84 | MAPT (0.33) | MAPK8MAPTEDNRBEDNRAKMT2A | |
| SCHEMBL3817284 | 0.80 | MAPK8 (0.41) | MAPK8MAPTACACBKMT2AALDH1A1 | |
| SCHEMBL686300 | 0.78 | KMT2A (0.32) | MAPTKMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL18952326 | 0.77 | MAPK8 (0.57) | MAPK8MAPTEDNRBEDNRAGLA | |
| SCHEMBL2012249 | 0.76 | MAPK8 (0.52) | MAPK8MAPTACACBKMT2AL3MBTL1 | |
| SCHEMBL8393570 | 0.75 | SORT1 (0.37) | KMT2AL3MBTL1ALDH1A1LMNAKDM4E | |
| SCHEMBL1505810 | 0.74 | LMNA (0.37) | MAPTKMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL7241544 | 0.74 | MAPK8 (0.39) | MAPK8MAPTACACBALDH1A1 | |
| SCHEMBL1436442 | 0.74 | MAPK8 (0.38) | MAPK8ACACBKMT2ALMNACYP1A2 | |
| SCHEMBL9565270 | 0.73 | PLAAT3 (0.37) | NPSR1L3MBTL1ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552760-A1 | Microbiological process for the preparation of 2-halopyrimidine-4-carboxylic acids | LONZA AG (CH) | 1993-07-28 | — | — | EP | disclosed |