SCHEMBL95656

SCHEMBL95656

Cc1cc(CO)cc(C)c1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.46
SHBG P04278 1/20 0.43
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
S1PR4 O95977 2/20 0.35
TSHR P16473 1/20 0.35
KDM4E B2RXH2 2/20 0.34
CASP6 P55212 1/20 0.34
MAPT P10636 1/20 0.34
RAPGEF4 Q8WZA2 1/20 0.33
CYP2A6 P11509 1/20 0.33
S1PR2 O95136 1/20 0.33
ALDH1A1 P00352 1/20 0.32
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HMGB1 P09429 1/20 0.31
CXCL12 P48061 1/20 0.31
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15957652 0.85 SHBG (0.52) ACHESHBGESR1ESR2KDM4E
SCHEMBL9369186 0.83 ACHE (0.37) ACHESHBGESR1ESR2TSHR
SCHEMBL13199148 0.80 ACHE (0.43) ACHESHBGESR1ESR2S1PR4
SCHEMBL670778 0.80 SHBG (0.58) ACHESHBGESR1ESR2KDM4E
SCHEMBL19628275 0.79 HSD17B10 (0.41) TSHRMAPTALDH1A1HSD17B10PTGS2
SCHEMBL21155542 0.78 ACHE (0.42) ACHESHBGESR1ESR2S1PR4
SCHEMBL9026840 0.78 TDP1 (0.40) SHBGESR1ESR2KDM4EMAPT
SCHEMBL5610638 0.78 ALDH1A1 (0.50) ACHESHBGESR1ESR2TSHR
SCHEMBL16104662 0.78 ACHE (0.42) ACHESHBGESR1ESR2S1PR4
SCHEMBL16960741 0.78 ACHE (0.42) ACHESHBGESR1ESR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 538 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621044-A Method for preparing bibenzyl compound 中国科学院大连化学物理研究所 2022-06-14 CN claimed
US-12577355-B2 Polyester polymer compositions CELANESE SALES GERMANY GMBH (DE) 2026-03-17 US disclosed
US-20250382443-A1 Polyamide Composition having a Reduced Density TICONA LLC (US) 2025-12-18 US disclosed
US-12371828-B2 CD extensible nonwoven composite KIMBERLY-CLARK WORLDWIDE, INC. (US) 2025-07-29 US disclosed
EP-4574904-A2 FLAME RESISTANT POLYMER COMPOSITION AND ARTICLES MADE THEREFROM Celanese International Corporation (US) 2025-06-25 EP disclosed
US-20250188270-A1 Thermoplastic Copolyester Elastomer Toughened Polyester CELANESE POLYMERS HOLDING, INC. 2025-06-12 US disclosed
EP-3990549-B1 FLAME RESISTANT POLYMER COMPOSITION AND ARTICLES MADE THEREFROM CELANESE INT CORP (US) 2025-05-14 EP disclosed
CN-119931278-A Polyester polymer composition 塞拉尼斯销售德国有限公司 2025-05-06 CN disclosed
US-12294185-B2 Electrical connector formed from a polymer composition having a low dielectric constant and dissipation factor TICONA LLC (US) 2025-05-06 US disclosed
CN-114341269-B Flame retardant polymer composition and articles made therefrom 国际人造丝公司 2025-04-15 CN disclosed
EP-0587311-A1 Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1994-03-16 EP disclosed
EP-0251827-B1 NEW CYCLIC ETHER DERIVATIVES, THEIR PREPARATION AND THEIR USE Sankyo Company Limited (JP) 1993-09-15 EP disclosed
US-5164436-A Mold release agents for clear thermoplastic resins HOECHST AKTIENGESELLSCHAFT (DE) 1992-11-17 US disclosed
EP-0291872-B1 WAX-LIKE COMPOUNDS OF AROMATIC ALCOHOLS AND THEIR APPLICATION HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-26 EP disclosed
EP-0498680-A1 New beta-amino-alpha-hydroxycarboxylic acids and their use Sankyo Company Limited (JP) 1992-08-12 EP disclosed
US-5091531-A Antitumor agents BURROUGHS WELLCOME CO. (US) 1992-02-25 US disclosed
US-4891363-A PLATELET ACTIVATING FACTOR ANTAGONISTS SANKYO COMPANY LIMITED (JP) 1990-01-02 US disclosed
EP-0305093-A1 Imidazo(1,2-b)pyridazine derivatives THE WELLCOME FOUNDATION LIMITED (GB) 1989-03-01 EP disclosed
EP-0291872-A2 Wax-like compounds of aromatic alcohols and their application HOECHST AKTIENGESELLSCHAFT (DE) 1988-11-23 EP disclosed
EP-0251827-A2 New cyclic ether derivatives, their preparation and their use Sankyo Company Limited (JP) 1988-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577355-B2 Polyester polymer compositions SMCHD1, PWWP2B, USP30 ACHE 4125/4885SHBG 3547/4885ESR1 1958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.