Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565715 | 0.86 | MEN1 (0.55) | EEF2KSRCCYP2C9CYP1A2MAPT | |
| SCHEMBL9565714 | 0.86 | MEN1 (0.55) | EEF2KSRCCYP2C9CYP1A2MAPT | |
| SCHEMBL9565770 | 0.83 | MAPT (0.43) | EEF2KSRCMAPTGAAMEN1 | |
| SCHEMBL9565774 | 0.83 | MAPT (0.43) | EEF2KSRCMAPTGAAMEN1 | |
| SCHEMBL8895510 | 0.73 | PTGS2 (0.56) | CYP2C9CYP1A2MAPTHTTGAA | |
| SCHEMBL8933323 | 0.73 | PTGS2 (0.56) | CYP2C9CYP1A2MAPTHTTGAA | |
| SCHEMBL9565732 | 0.72 | EEF2K (0.57) | EEF2KSRCCYP2C9CYP1A2GAA | |
| SCHEMBL9565698 | 0.71 | EEF2K (0.52) | EEF2KSRCCYP2C9CYP1A2MAPT | |
| SCHEMBL8582975 | 0.70 | CYP1A2 (0.47) | EEF2KSRCCYP2C9CYP1A2GAA | |
| SCHEMBL9565699 | 0.69 | SIRT1 (0.52) | EEF2KSRCCYP2C9CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546661-A1 | Pyrimidine derivatives, method for preparation thereof and pharmaceutical composition having said derivatives as active elements | JAPAN ENERGY CORPORATION (JP) | 1993-06-16 | — | — | EP | disclosed |