Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | EEF2K | O00418 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565730 | 1.00 | LRRK2 (0.46) | LRRK2ERO1AALOX5PTGS1PTGS2 | |
| SCHEMBL9565687 | 0.88 | SIRT1 (0.54) | ALOX5PTGS1PTGS2EEF2KSRC | |
| SCHEMBL9565688 | 0.88 | SIRT1 (0.54) | ALOX5PTGS1PTGS2EEF2KSRC | |
| SCHEMBL9565691 | 0.74 | MEN1 (0.48) | PTGS1PTGS2EEF2KSRCSIRT1 | |
| SCHEMBL9565692 | 0.74 | MEN1 (0.48) | PTGS1PTGS2EEF2KSRCSIRT1 | |
| SCHEMBL9129353 | 0.72 | SIRT1 (0.57) | ALOX5PTGS1PTGS2EEF2KSRC | |
| SCHEMBL9565707 | 0.72 | MAPT (0.68) | SIRT1KMT2AMEN1GAAMAPT | |
| SCHEMBL9565708 | 0.72 | MAPT (0.68) | SIRT1KMT2AMEN1GAAMAPT | |
| SCHEMBL9129357 | 0.72 | SIRT1 (0.57) | ALOX5PTGS1PTGS2EEF2KSRC | |
| SCHEMBL11387780 | 0.72 | MEN1 (0.50) | KMT2AMEN1MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546661-A1 | Pyrimidine derivatives, method for preparation thereof and pharmaceutical composition having said derivatives as active elements | JAPAN ENERGY CORPORATION (JP) | 1993-06-16 | — | — | EP | disclosed |