Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.79 |
| ▸ | DRD3 | P35462 | 2/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 6/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9559590 | 0.90 | KDM4E (0.68) | DRD2DRD3KDM4ELMNAHTR1A | |
| SCHEMBL1193545 | 0.88 | DRD2 (1.00) | DRD2DRD3 | |
| SCHEMBL11273863 | 0.88 | KDM4E (0.70) | DRD2DRD3KDM4ELMNAHTR1A | |
| SCHEMBL11745974 | 0.85 | DRD2 (0.73) | DRD2DRD3KDM4ELMNAHTR1A | |
| SCHEMBL9646379 | 0.84 | KDM4E (0.64) | DRD2DRD3KDM4ELMNAHTR1A | |
| SCHEMBL2092966 | 0.82 | KDM4E (0.62) | DRD2DRD3KDM4ELMNAHTR1A | |
| SCHEMBL9347278 | 0.82 | KDM4E (0.62) | DRD2DRD3KDM4ELMNAHTR1A | |
| SCHEMBL10367403 | 0.81 | ADRA1B (0.63) | DRD2DRD3LMNAHTR1AADRA1B | |
| SCHEMBL6748972 | 0.81 | TSHR (0.61) | DRD2DRD3KDM4ELMNAALDH1A1 | |
| SCHEMBL7289302 | 0.81 | DRD2 (0.58) | DRD2DRD3HTR1AADRA1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548798-A1 | Antiviral agent | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |
| EP-0094159-B1 | DIHYDROPYRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-03-14 | — | — | EP | disclosed |
| US-4892875-A | HYPOTENSIVE, RENAL VASODILATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0094159-A1 | Dihydropyridine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1983-11-16 | — | — | EP | disclosed |