SCHEMBL9565871

SCHEMBL9565871

O=C(c1ccccc1O)N1CCN(c2ccccc2Cl)CC1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.57
TSHR P16473 2/20 0.57
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
MAPT P10636 1/20 0.56
AVPR1A P37288 1/20 0.55
AKR1C3 P42330 1/20 0.55
RAB9A P51151 2/20 0.54
MGLL Q99685 1/20 0.54
MAPK1 P28482 1/20 0.54
GFER P55789 1/20 0.54
GPR6 P46095 1/20 0.54
ALDH1A1 P00352 3/20 0.53
KDM4E B2RXH2 1/20 0.53
HPGD P15428 1/20 0.53
HSD17B10 Q99714 1/20 0.53
HSP90AA1 P07900 1/20 0.53
NPSR1 Q6W5P4 2/20 0.53
GLA P06280 1/20 0.53
GAA P10253 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23064276 0.85 GAA (0.67) SMN1; SMN2TSHRMEN1KMT2AMAPT
SCHEMBL11718417 0.83 MEN1 (0.61) SMN1; SMN2TSHRMEN1KMT2AMAPT
SCHEMBL31347868 0.83 MEN1 (0.61) SMN1; SMN2TSHRMEN1KMT2AMAPT
SCHEMBL23283028 0.82 KDM4E (0.52) SMN1; SMN2MEN1KMT2AMAPTAKR1C3
SCHEMBL9565911 0.80 ALDH1A1 (0.81) SMN1; SMN2TSHRMEN1KMT2AMAPT
SCHEMBL21987068 0.80 MEN1 (0.72) SMN1; SMN2MEN1KMT2AMAPTAKR1C3
SCHEMBL23064287 0.80 GAA (0.67) SMN1; SMN2MEN1KMT2AMAPTAVPR1A
SCHEMBL26669423 0.79 P2RX7 (0.69) SMN1; SMN2MEN1KMT2AMAPTAVPR1A
SCHEMBL10723816 0.78 RAB9A (0.80) MEN1KMT2ARAB9AMGLLALDH1A1
SCHEMBL8240451 0.78 ALDH1A1 (0.60) SMN1; SMN2TSHRMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0548798-A1 Antiviral agent SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1993-06-30 EP disclosed