Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.61 |
| ▸ | HPGD | P15428 | 7/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1202541 | 0.79 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL10677544 | 0.78 | HSD17B10 (0.53) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL14219778 | 0.78 | KMT2A (0.53) | ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL196585 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL11374040 | 0.76 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL2061977 | 0.76 | ALDH1A1 (0.69) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL28160698 | 0.76 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL4062229 | 0.76 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL6371982 | 0.75 | KDM4E (0.64) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL31267447 | 0.75 | ALDH1A1 (0.68) | ALDH1A1KDM4EHPGDHSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1081438-A | Imdazole derivatives and preparation method thereof and the application on therapeutics | FOURNIER IND & SANTE (FR) | 1994-02-02 | — | — | CN | disclosed |
| EP-0564356-A1 | 4-phenylaminomethylimidazole derivatives, process for their preparation, angiotensin II receptor antagonists and their application in therapy | FOURNIER INDUSTRIE ET SANTE (FR) | 1993-10-06 | — | — | EP | disclosed |