SCHEMBL4062229

SCHEMBL4062229

Nc1ccccc1C(=O)NCC(=O)O.[NaH]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.54
KDM4E B2RXH2 9/20 0.54
HPGD P15428 7/20 0.54
KEAP1 Q14145 1/20 0.53
MAPT P10636 2/20 0.51
HIF1A Q16665 1/20 0.51
SLC22A6 Q4U2R8 1/20 0.51
SLC22A8 Q8TCC7 1/20 0.51
HSD17B10 Q99714 3/20 0.50
NSD2 O96028 2/20 0.50
RCE1 Q9Y256 1/20 0.50
TP53 P04637 1/20 0.48
MAPK1 P28482 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
GAA P10253 1/20 0.47
USP2 O75604 1/20 0.47
EGLN1 Q9GZT9 1/20 0.47
HDAC1 Q13547 1/20 0.47
CFTR P13569 1/20 0.46
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28160698 1.00 ALDH1A1 (0.54) ALDH1A1KDM4EHPGDKEAP1MAPT
SCHEMBL196585 0.98 ALDH1A1 (0.55) ALDH1A1KDM4EHPGDKEAP1MAPT
SCHEMBL31448014 0.85 KEAP1 (0.62) KDM4EKEAP1MAPTHIF1ASLC22A6
SCHEMBL12311981 0.84 MMP2 (0.59) ALDH1A1KDM4EHPGDKEAP1MAPT
SCHEMBL15630971 0.81 KEAP1 (0.49) ALDH1A1KDM4EHPGDKEAP1MAPT
SCHEMBL8745364 0.81 ALDH1A1 (0.60) ALDH1A1KDM4EHPGDMAPTHSD17B10
SCHEMBL31267447 0.81 ALDH1A1 (0.68) ALDH1A1KDM4EHPGDHSD17B10NSD2
SCHEMBL233364 0.81 ALDH1A1 (0.53) ALDH1A1KDM4EHPGDHSD17B10NSD2
SCHEMBL4955428 0.81 ALDH1A1 (0.59) ALDH1A1KDM4EHPGDHSD17B10NSD2
Aminohippuric Acid SCHEMBL8351356 0.80 MAPT (0.71) ALDH1A1KDM4EKEAP1MAPTHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114126654-A Para-aminohippuric acid (PAH) as a kidney protective substance 同位素技术慕尼黑有限公司 2022-03-01 CN claimed
CN-104725628-B A kind of single functionalization branched polyethylene glycol, preparation method and its bio-related substance containing degradable group 厦门赛诺邦格生物科技股份有限公司 2018-04-17 CN claimed
CN-104877127-B A kind of eight arms polyethyleneglycol derivative, preparation method and its bio-related substance of modification 厦门赛诺邦格生物科技股份有限公司 2017-11-10 CN claimed
CN-104530413-B A kind of bio-related substance of multiple functionalized H types polyethyleneglycol derivative modification 厦门赛诺邦格生物科技股份有限公司 2017-08-25 CN claimed
CN-104109235-B A kind of single functionalized poly (ethylene glycol), preparation method and its bio-related substance with nitrogen-atoms branch centers 厦门赛诺邦格生物科技股份有限公司 2017-07-18 CN claimed
CN-104877127-A Eight-armed polyethylene glycol derivative, preparation method and related biological substance modified by derivative XIAMEN SINOPEG BIOTECH CO LTD 2015-09-02 CN claimed
CN-104725628-A Single functional branched polyethylene glycol containing degradable radical, preparation method and biorelevant substance of single functional branched polyethylene glycol XIAMEN SINOPEG BIOTECH CO LTD 2015-06-24 CN claimed
CN-104530413-A Biologically related substances modified by multifunctional H-type polyethylene glycol derivative XIAMEN SINOPEG BIOTECH INC 2015-04-22 CN claimed
CN-104109235-A Mono-functionalized polyethylene glycol with nitrogen atom branched center and its preparation method and biologically-relevant matter XIAMEN SINOPEG BIOTECH CO LTD 2014-10-22 CN claimed
WO-2008116165-A9 METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION NEXT SAFETY INC (US) 2009-06-11 WO claimed
WO-2008116165-A2 METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION NEXT SAFETY, INC. (US) 2008-09-25 WO claimed
US-20080066741-A1 METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION HUNTER, CHARLES ERIC 2008-03-20 US claimed
US-12517120-B2 Glucose-6-phosphate dehydrogenase mutant and use thereof in preparing detection reagent BEIJING STRONG BIOTECHNOLOGIES, INC. (CN) 2026-01-06 US disclosed
US-20240123168-A1 PRODUCT DELIVERY DEVICES AND METHODS MUSTAPHA JIHAD A (US) 2024-04-18 US disclosed
US-20230414796-A1 COMBINATION OF PARA-AMINOHIPPURIC ACID (PAH) AND RADIOLABELED COMPLEXES FOR TREATING CANCER ITM Isotope Technologies Munich SE (DE) 2023-12-28 US disclosed
CN-117279681-A Product delivery device and method 呼吸解决方案股份有限公司 2023-12-22 CN disclosed
CN-101553210-A Method and system for delivering a drug via inhalation NEXT SAFETY INC (US) 2009-10-07 CN disclosed
CN-101296691-A transdermal drug delivery dosage form NUVO RES INC (CA) 2008-10-29 CN disclosed
US-20080066741-A1 METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION HUNTER, CHARLES ERIC 2008-03-20 US disclosed
CN-1925875-A Chemically modified small molecules NEKTAR THERAPEUTICS AL CORP (US) 2007-03-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230414796-A1 COMBINATION OF PARA-AMINOHIPPURIC ACID (PAH) AND RADIOLABELED COMPLEXES FOR TREATING CANCER PAH, VHL, SLC10A6 ALDH1A1 601/4885KDM4E 1606/4885HPGD 802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.