Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | DRD1 | P21728 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | DRD5 | P21918 | 3/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566161 | 0.85 | PSEN1 (0.35) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL9565985 | 0.77 | CYP11B1 (0.34) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL9566100 | 0.77 | ALDH1A1 (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9566056 | 0.74 | CYP11B1 (0.34) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8540709 | 0.74 | ENPP1 (0.38) | DRD2DRD3DRD4PSEN1PSEN2 | |
| SCHEMBL9175055 | 0.74 | ENPP1 (0.39) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL10969416 | 0.74 | GAA (0.38) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL11231034 | 0.74 | GAA (0.38) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL9565958 | 0.74 | DRD2 (0.35) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL9566039 | 0.73 | ENPP1 (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566534-A1 | Derivatives of benzophenone | CIBA-GEIGY AG (CH) | 1993-10-20 | — | — | EP | disclosed |