Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 3/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | FABP2 | P12104 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566100 | 0.86 | ALDH1A1 (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9566151 | 0.85 | DRD2 (0.36) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9565958 | 0.84 | DRD2 (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8540709 | 0.81 | ENPP1 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9175055 | 0.80 | ENPP1 (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL10969416 | 0.80 | GAA (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11231034 | 0.80 | GAA (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9565985 | 0.79 | CYP11B1 (0.34) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9566056 | 0.78 | CYP11B1 (0.34) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9566039 | 0.77 | ENPP1 (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566534-A1 | Derivatives of benzophenone | CIBA-GEIGY AG (CH) | 1993-10-20 | — | — | EP | disclosed |