Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1160393 | 0.95 | NQO1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7589943 | 0.94 | NQO1 (0.33) | — | |
| SCHEMBL27375147 | 0.72 | NQO1 (0.32) | — | |
| SCHEMBL9057236 | 0.69 | NQO1 (0.33) | — | |
| SCHEMBL30753234 | 0.67 | — | — | |
| SCHEMBL29486506 | 0.67 | — | — | |
| SCHEMBL3309437 | 0.66 | GRIN2D (0.34) | — | |
| SCHEMBL10782968 | 0.66 | GSTP1 (0.32) | — | |
| SCHEMBL30677472 | 0.64 | ALDH1A1 (0.33) | — | |
| Anthracene SCHEMBL21582023 | 0.63 | LMNA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536515-A1 | Novel 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID COMPANY (US) | 1993-04-14 | — | — | EP | disclosed |
| EP-0535346-A1 | 9-amino-7-substituted-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID COMPANY (US) | 1993-04-07 | — | — | EP | disclosed |