Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | S100A4 | P26447 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566568 | 0.83 | S100A4 (0.41) | TDP1ALDH1A1S100A4RECQLPDE10A | |
| SCHEMBL6051840 | 0.80 | TSHR (0.69) | TSHRSMN1; SMN2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL28009614 | 0.77 | TSHR (0.51) | TSHRSMN1; SMN2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL9566483 | 0.75 | ALDH1A1 (0.52) | SMN1; SMN2TDP1ALDH1A1L3MBTL1S100A4 | |
| SCHEMBL27930468 | 0.73 | TSHR (0.55) | TSHRSMN1; SMN2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL5460079 | 0.73 | TSHR (0.64) | TSHRSMN1; SMN2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL114004 | 0.73 | TSHR (0.64) | TSHRSMN1; SMN2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL8369010 | 0.73 | HSD17B10 (0.62) | TSHRSMN1; SMN2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL19608973 | 0.73 | HSD17B10 (0.62) | TSHRSMN1; SMN2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL10711629 | 0.72 | HSD17B10 (0.56) | TSHRSMN1; SMN2HSD17B10TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563386-A1 | ANTICANCER COMPOSITION AND COMPOUND | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-10-06 | — | — | EP | disclosed |