Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4523309 | 1.00 | SIGMAR1 (0.56) | SIGMAR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9566495 | 0.93 | KDM4E (0.53) | SIGMAR1CYP3A4CYP2D6ALDH1A1KDM4E | |
| SCHEMBL30803151 | 0.88 | CYP2D6 (0.50) | SIGMAR1CYP3A4CYP2D6ALDH1A1MEN1 | |
| SCHEMBL20455789 | 0.86 | ALDH1A1 (0.51) | SIGMAR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4509900 | 0.83 | ALDH1A1 (0.50) | SIGMAR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30751751 | 0.81 | L3MBTL1 (0.49) | SIGMAR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22864682 | 0.81 | L3MBTL1 (0.49) | SIGMAR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30751712 | 0.81 | SIGMAR1 (0.48) | SIGMAR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9566374 | 0.81 | MEN1 (0.48) | SIGMAR1CYP2C9CYP2C19ALDH1A1GAA | |
| SCHEMBL16053764 | 0.80 | L3MBTL1 (0.48) | SIGMAR1CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550025-A1 | Azaspiroheptanes and octanes and processes for their production | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |