Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SI | P14410 | 1/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983254 | 0.98 | MAPT (0.61) | MAPTLMNATDP1ALDH1A1NPC1 | |
| SCHEMBL8129593 | 0.90 | MAPT (0.54) | MAPTLMNATDP1NPC1RAB9A | |
| SCHEMBL8129591 | 0.90 | MAPT (0.54) | MAPTLMNATDP1NPC1RAB9A | |
| SCHEMBL29769219 | 0.86 | XDH (0.58) | MAPTLMNATDP1ALDH1A1NPC1 | |
| SCHEMBL18541587 | 0.84 | NPSR1 (0.50) | MAPTLMNATDP1ALDH1A1NPC1 | |
| SCHEMBL18538212 | 0.81 | MAPT (0.43) | MAPTLMNATDP1NPC1RAB9A | |
| SCHEMBL670531 | 0.79 | LMNA (0.60) | MAPTLMNATDP1ALDH1A1NPC1 | |
| SCHEMBL22604036 | 0.78 | MAPK1 (0.62) | MAPTLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL28880529 | 0.78 | RAB9A (0.76) | MAPTALDH1A1NPC1RAB9APOLB | |
| SCHEMBL12496111 | 0.78 | MAPT (0.54) | MAPTLMNATDP1ALDH1A1MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823099-A | Preparation method of gedali plug | 浙江大学衢州研究院 | 2025-04-15 | — | — | CN | disclosed |
| CN-118745159-A | Preparation method of Gedatolisib key intermediate | 浙江大学衢州研究院 | 2024-10-08 | — | — | CN | disclosed |
| CN-118745169-A | Preparation method of 4- (4, 6-dimorphine-1, 3, 5-triazine-2-yl) aniline and intermediate thereof | 浙江大学衢州研究院 | 2024-10-08 | — | — | CN | disclosed |
| CN-112697897-B | Derivatization reagent and application thereof | 中国药科大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-112697897-A | Derivatization reagent and application thereof | 中国药科大学 | 2021-04-23 | — | — | CN | disclosed |
| EP-0563386-A1 | ANTICANCER COMPOSITION AND COMPOUND | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-10-06 | — | — | EP | disclosed |