Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | CDK9 | P50750 | 3/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566577 | 0.88 | NPC1 (0.54) | HTR2BPDE4DCDK9NPC1RAB9A | |
| SCHEMBL9566528 | 0.81 | NPC1 (0.56) | ADORA3ADORA1NPC1RAB9ALMNA | |
| SCHEMBL8413057 | 0.80 | CDK9 (0.77) | HTR2BPDE4DCDK9ADORA3ACKR3 | |
| SCHEMBL8413500 | 0.79 | HTR2B (0.58) | HTR2BPDE4DCDK9ACKR3NPC1 | |
| SCHEMBL10483482 | 0.78 | MEN1 (0.55) | CDK9NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL9564262 | 0.78 | ADORA1 (0.60) | ADORA3ADORA1NPC1RAB9ALMNA | |
| SCHEMBL8413880 | 0.78 | GPR68 (0.64) | HTR2BPDE4DCDK9ACKR3NPC1 | |
| SCHEMBL3945635 | 0.77 | ADORA1 (0.60) | ADORA3ADORA1LMNASMN1; SMN2USP2 | |
| SCHEMBL8413934 | 0.77 | HTR2B (0.58) | HTR2BPDE4DCDK9ACKR3NPC1 | |
| SCHEMBL9566451 | 0.76 | SMN1; SMN2 (0.56) | NPC1RAB9ALMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563386-A1 | ANTICANCER COMPOSITION AND COMPOUND | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-10-06 | — | — | EP | disclosed |