Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17156499 | 0.86 | HRH4 (0.50) | HRH4ADORA2APOLBADORA3ADORA2B | |
| SCHEMBL17156503 | 0.82 | HSP90AA1 (0.58) | HRH4ADORA2APOLBADORA3ADORA2B | |
| SCHEMBL28303830 | 0.80 | NPC1 (0.62) | HRH4ADORA2APOLBADORA3ADORA2B | |
| SCHEMBL17164333 | 0.76 | HRH4 (0.45) | HRH4RAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL669913 | 0.76 | SMN1; SMN2 (0.59) | ADORA2APOLBADORA3ADORA2BADORA1 | |
| SCHEMBL29803060 | 0.76 | SMN1; SMN2 (0.59) | ADORA2APOLBADORA3ADORA2BADORA1 | |
| SCHEMBL9566567 | 0.73 | RAB9A (0.48) | ADORA2APOLBADORA3ADORA2BADORA1 | |
| SCHEMBL28136263 | 0.73 | MEN1 (0.42) | HRH4RAB9ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL25587161 | 0.73 | HRH4 (0.41) | HRH4RAB9ASMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL10203915 | 0.73 | RAB9A (0.44) | HRH4RAB9ASMN1; SMN2L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563386-A1 | ANTICANCER COMPOSITION AND COMPOUND | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-10-06 | — | — | EP | disclosed |