Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566568 | 0.79 | S100A4 (0.41) | KDM4E | |
| SCHEMBL4028544 | 0.77 | CYP2D6 (0.54) | RAB9ANPC1HTR2BPDE4DHSP90AA1 | |
| SCHEMBL29808150 | 0.76 | HSP90AA1 (0.69) | RAB9ANPC1HTR2BPDE4DPOLB | |
| SCHEMBL2490905 | 0.76 | HSP90AA1 (0.69) | RAB9ANPC1HTR2BPDE4DPOLB | |
| SCHEMBL375767 | 0.74 | LMNA (0.39) | — | |
| SCHEMBL9566587 | 0.73 | HRH4 (0.57) | RAB9ANPC1HTR2BPOLBADORA3 | |
| SCHEMBL22468041 | 0.73 | LMNA (0.43) | RAB9ANPC1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL18920567 | 0.72 | CYP1A2 (0.43) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20252178 | 0.71 | MEN1 (0.50) | RAB9ANPC1POLBADORA3ADORA2A | |
| SCHEMBL125432 | 0.71 | TSHR (0.39) | HSP90AA1SRCFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563386-A1 | ANTICANCER COMPOSITION AND COMPOUND | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-10-06 | — | — | EP | disclosed |