Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BCL6 | P41182 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12277332 | 0.80 | PTGES (0.40) | MEN1KMT2AALOX5APFEN1TYK2 | |
| SCHEMBL20654332 | 0.80 | L3MBTL1 (0.43) | TYK2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2409693 | 0.78 | MEN1 (0.47) | MEN1KMT2AALOX5APFEN1BACE1 | |
| SCHEMBL12578987 | 0.78 | RAB9A (0.41) | HRH4TYK2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28300766 | 0.78 | TYK2 (0.37) | MEN1KMT2AALOX5APFEN1HRH4 | |
| SCHEMBL20654333 | 0.77 | NPC1 (0.59) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12452238 | 0.74 | NPC1 (0.39) | ALOX5APFEN1HRH4TYK2BACE1 | |
| SCHEMBL9566587 | 0.73 | HRH4 (0.57) | HRH4BACE1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4389561 | 0.72 | NPC1 (0.58) | MEN1KMT2AALOX5APFEN1NPC1 | |
| SCHEMBL8372471 | 0.72 | TTR (0.41) | HRH4TYK2BACE1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334546-B | Novel ring-substituted N-pyridyl amides as kinase inhibitors | 诺华股份有限公司 | 2017-05-03 | — | — | CN | disclosed |