SCHEMBL9566595

SCHEMBL9566595

O=C1NC(=O)c2cc(Nc3cccc(I)c3)ccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRAF P15056 3/20 0.49
KDM4E B2RXH2 4/20 0.48
ALDH1A1 P00352 4/20 0.48
GLA P06280 2/20 0.48
KMT2A Q03164 5/20 0.47
MEN1 O00255 4/20 0.47
HPGD P15428 2/20 0.47
MAPT P10636 2/20 0.47
RGS12 O14924 1/20 0.47
GMNN O75496 1/20 0.47
PRKD3 O94806 1/20 0.47
EGFR P00533 1/20 0.47
LMNA P02545 1/20 0.47
PRKCG P05129 1/20 0.47
PRKCB P05771 1/20 0.47
CYP3A4 P08684 1/20 0.47
SRC P12931 1/20 0.47
PRKCA P17252 1/20 0.47
NFKB1 P19838 1/20 0.47
PRKCH P24723 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8834415 0.85 BRAF (0.67) BRAFKDM4EALDH1A1GLAKMT2A
SCHEMBL9566667 0.85 APP (0.61) KDM4EALDH1A1GLAKMT2AMEN1
SCHEMBL27369690 0.83 EGFR (0.68) BRAFKDM4EALDH1A1GLAKMT2A
SCHEMBL9566671 0.81 ATM (0.55) BRAFKDM4EALDH1A1GLAKMT2A
SCHEMBL9566647 0.77 MEN1 (0.53) KDM4EALDH1A1GLAKMT2AMEN1
SCHEMBL9566654 0.77 KDM4E (0.49) BRAFKDM4EALDH1A1GLAKMT2A
SCHEMBL1686500 0.76 MEN1 (0.55) KDM4EALDH1A1KMT2AMEN1MAPT
SCHEMBL9566653 0.75 KMT2A (0.49) KDM4EALDH1A1GLAKMT2AMEN1
SCHEMBL10600683 0.75 PPOX (0.69) KDM4EALDH1A1GLAKMT2AMEN1
SCHEMBL27697134 0.75 EGFR (0.72) KDM4EALDH1A1GLAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530707-A1 Method for preparing polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP claimed
EP-0530707-A1 Method for preparing polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP disclosed