SCHEMBL9566671

SCHEMBL9566671

Nc1cccc(Nc2ccc3c(c2)C(=O)NC3=O)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.55
KMT2A Q03164 5/20 0.53
KDM4E B2RXH2 5/20 0.53
MEN1 O00255 4/20 0.53
LMNA P02545 2/20 0.53
MAPT P10636 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
GAA P10253 1/20 0.53
GFER P55789 1/20 0.53
BRAF P15056 2/20 0.49
MAPK14 Q16539 2/20 0.48
ALDH1A1 P00352 4/20 0.47
HPGD P15428 3/20 0.47
GLA P06280 2/20 0.47
RGS12 O14924 1/20 0.47
GMNN O75496 1/20 0.47
PRKD3 O94806 1/20 0.47
EGFR P00533 1/20 0.47
PRKCG P05129 1/20 0.47
PRKCB P05771 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14514337 0.85 DDX3X (0.66) ATMKMT2AKDM4EMEN1LMNA
SCHEMBL9566653 0.85 KMT2A (0.49) ATMKMT2AKDM4EMEN1LMNA
SCHEMBL9566666 0.83 ATM (0.75) ATMKMT2AMEN1MAPTALDH1A1
SCHEMBL27369690 0.83 EGFR (0.68) KMT2AKDM4EMEN1LMNAMAPT
SCHEMBL9566646 0.82 PBRM1 (0.50) ATMKMT2AKDM4EMEN1LMNA
Diphenylamine SCHEMBL27637720 0.82 ALDH1A1 (0.62) ATMKMT2AKDM4EMEN1LMNA
SCHEMBL29664046 0.81 MAPK14 (0.58) KMT2AKDM4EMEN1LMNAMAPT
SCHEMBL9566595 0.81 BRAF (0.49) KMT2AKDM4EMEN1LMNAMAPT
SCHEMBL9566643 0.77 KDM4E (0.49) ATMKMT2AKDM4EMEN1LMNA
SCHEMBL3145102 0.77 PPOX (0.55) KMT2AKDM4EMEN1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530707-A1 Method for preparing polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP claimed
EP-0530707-A1 Method for preparing polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP disclosed