Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595728 | 0.83 | MAPT (0.41) | THRATHRBHTTMAPTKDM4E | |
| SCHEMBL8589991 | 0.82 | RARB (0.48) | THRATHRBHTTMAPTRARB | |
| SCHEMBL8990656 | 0.81 | PLA2G2A (0.45) | THRATHRBRARB | |
| SCHEMBL8593509 | 0.80 | TSHR (0.44) | THRBHTTMAPTKDM4EALDH1A1 | |
| SCHEMBL9566681 | 0.79 | PLA2G2A (0.48) | THRATHRBRARB | |
| SCHEMBL7007318 | 0.76 | ALDH1A1 (0.46) | HTTMAPTKDM4EALDH1A1 | |
| SCHEMBL607945 | 0.74 | HSD17B10 (0.44) | MAPK1HTTMAPTKDM4EALDH1A1 | |
| SCHEMBL8946844 | 0.74 | MAPT (0.41) | HTTMAPTKDM4EALDH1A1GAA | |
| SCHEMBL2831144 | 0.74 | HSD17B10 (0.39) | MAPK1HTTMAPTKDM4EHSD17B10 | |
| SCHEMBL5648170 | 0.73 | MAPK1 (0.59) | MAPK1HTTRARBEPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545866-A1 | Process for the preparation of trifluorobenzol derivatives | CIBA-GEIGY AG (CH) | 1993-06-09 | — | — | EP | disclosed |