Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804048 | 0.84 | KEAP1 (0.37) | ALDH1A1KMT2AKEAP1NFE2L2MAPT | |
| SCHEMBL8946849 | 0.81 | KEAP1 (0.35) | ALDH1A1KEAP1NFE2L2MAPTKDM4E | |
| SCHEMBL607945 | 0.80 | HSD17B10 (0.44) | ALDH1A1KMT2AKEAP1NFE2L2MAPT | |
| SCHEMBL2831144 | 0.80 | HSD17B10 (0.39) | KMT2AKEAP1NFE2L2MAPTKDM4E | |
| SCHEMBL11916149 | 0.79 | SLC6A2 (0.38) | ALDH1A1MAPTKDM4EHTT | |
| SCHEMBL9839630 | 0.79 | KDM4E (0.46) | ALDH1A1KEAP1NFE2L2MAPTKDM4E | |
| SCHEMBL27927680 | 0.79 | HSD17B10 (0.43) | ALDH1A1KMT2AKEAP1NFE2L2MAPT | |
| SCHEMBL9566698 | 0.76 | KEAP1 (0.32) | KEAP1NFE2L2MAPT | |
| SCHEMBL9566679 | 0.76 | THRA (0.46) | ALDH1A1MAPTKDM4EHTT | |
| Propylene Glycol SCHEMBL2834441 | 0.76 | HSD17B10 (0.36) | ALDH1A1KMT2AMAPTKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945435-B1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMA CO LTD (JP) | 2003-08-13 | — | — | EP | disclosed |
| US-6136823-A | BACTERICIDES OR VIRICIDES | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0945435-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |