Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517994 | 0.83 | P4HTM (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL9566758 | 0.83 | NPC1 (0.57) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL9515933 | 0.83 | P4HTM (0.55) | ALDH1A1GAAKMT2AP4HTMKDM4E | |
| SCHEMBL9566760 | 0.80 | RAB9A (0.60) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL9566737 | 0.78 | NPC1 (0.57) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL9515753 | 0.78 | GABRA5 (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL12020439 | 0.78 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9566777 | 0.78 | P4HTM (0.61) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL9537850 | 0.76 | ALDH1A1 (0.69) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9566756 | 0.76 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |