Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566817 | 0.89 | TRPV1 (0.55) | TRPV1KDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL9566892 | 0.87 | PLK1 (0.53) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9566756 | 0.87 | RAB9A (0.57) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9566836 | 0.87 | TRPV1 (0.59) | TRPV1KDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL9566731 | 0.86 | TRPV1 (0.56) | TRPV1KDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL9566861 | 0.85 | P4HTM (0.61) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9566843 | 0.84 | TRPV1 (0.54) | TRPV1KDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL9566738 | 0.84 | CXCR2 (0.64) | RAB9ANPC1MEN1KMT2ACXCR1 | |
| SCHEMBL9566848 | 0.84 | P4HTM (0.55) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9566837 | 0.83 | P4HTM (0.58) | KDM4ERAB9ANPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |