Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566731 | 0.90 | TRPV1 (0.56) | TRPV1ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL9566764 | 0.89 | TRPV1 (0.60) | TRPV1ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL9566843 | 0.88 | TRPV1 (0.54) | TRPV1ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL9566854 | 0.87 | TRPV1 (0.53) | TRPV1ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL9566841 | 0.86 | TRPV1 (0.60) | TRPV1ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL9566796 | 0.84 | LMNA (0.56) | ALDH1A1HPGDKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL9566836 | 0.84 | TRPV1 (0.59) | TRPV1ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL9566769 | 0.83 | KDM4E (0.57) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9566868 | 0.83 | CXCR2 (0.60) | ALDH1A1NPC1RAB9AP4HTM | |
| SCHEMBL9566825 | 0.83 | P4HTM (0.66) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |