Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.47 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566796 | 0.89 | LMNA (0.56) | PLK1FAAHRAB9ANR1H4SMN1; SMN2 | |
| SCHEMBL9566861 | 0.89 | P4HTM (0.61) | RAB9ASMN1; SMN2NPC1LMNAP4HTM | |
| SCHEMBL9566764 | 0.87 | TRPV1 (0.60) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL9566821 | 0.86 | NR1H4 (0.54) | PLK1FAAHRAB9ANR1H4SMN1; SMN2 | |
| SCHEMBL9566867 | 0.86 | LMNA (0.57) | PLK1FAAHRAB9ANR1H4SMN1; SMN2 | |
| SCHEMBL9566751 | 0.84 | NPC1 (0.52) | PLK1RAB9ANR1H4SMN1; SMN2NPC1 | |
| SCHEMBL9566756 | 0.84 | RAB9A (0.57) | RAB9ANR1H4SMN1; SMN2NPC1LMNA | |
| SCHEMBL9566884 | 0.84 | SMN1; SMN2 (0.55) | PLK1FAAHRAB9ANR1H4SMN1; SMN2 | |
| SCHEMBL9566790 | 0.83 | LMNA (0.59) | FAAHRAB9ANR1H4SMN1; SMN2NPC1 | |
| SCHEMBL9566871 | 0.82 | RAB9A (0.53) | RAB9ANR1H4SMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |