Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.49 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.49 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566866 | 0.88 | KDM4E (0.56) | KDM4EP4HTMKMT2AMEN1ALDH1A1 | |
| SCHEMBL9566825 | 0.88 | P4HTM (0.66) | KDM4EP4HTMKMT2AMEN1ALDH1A1 | |
| SCHEMBL9566868 | 0.88 | CXCR2 (0.60) | P4HTMALDH1A1RAB9ANPC1CXCR1 | |
| SCHEMBL9566851 | 0.87 | P4HTM (0.58) | KDM4EP4HTMKMT2AMEN1ALDH1A1 | |
| SCHEMBL9566737 | 0.87 | NPC1 (0.57) | KDM4EP4HTMKMT2AMEN1ALDH1A1 | |
| SCHEMBL9566795 | 0.86 | P4HTM (0.59) | P4HTMKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9566812 | 0.85 | P4HTM (0.59) | KDM4EP4HTMKMT2AMEN1ALDH1A1 | |
| SCHEMBL9566792 | 0.85 | P4HTM (0.55) | KDM4EP4HTMKMT2AMEN1ALDH1A1 | |
| SCHEMBL9566848 | 0.84 | P4HTM (0.55) | KDM4EP4HTMKMT2AMEN1ALDH1A1 | |
| SCHEMBL9566817 | 0.83 | TRPV1 (0.55) | KDM4EP4HTMALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |