Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566740 | 0.89 | CXCR2 (0.54) | P4HTMSMN1; SMN2LMNASTAT3ALDH1A1 | |
| SCHEMBL9566751 | 0.88 | NPC1 (0.52) | KDM4EP4HTMSMN1; SMN2LMNASTAT3 | |
| SCHEMBL9566769 | 0.88 | KDM4E (0.57) | KDM4EP4HTMSMN1; SMN2LMNARAB9A | |
| SCHEMBL9566779 | 0.87 | TP53 (0.55) | P4HTMSMN1; SMN2LMNARAB9AALDH1A1 | |
| SCHEMBL9566798 | 0.87 | MAPT (0.60) | KDM4EP4HTMSMN1; SMN2LMNASTAT3 | |
| SCHEMBL9566851 | 0.83 | P4HTM (0.58) | KDM4EP4HTMSMN1; SMN2LMNARAB9A | |
| SCHEMBL9566796 | 0.82 | LMNA (0.56) | KDM4EP4HTMSMN1; SMN2LMNASTAT3 | |
| SCHEMBL9566792 | 0.81 | P4HTM (0.55) | KDM4EP4HTMSMN1; SMN2LMNARAB9A | |
| SCHEMBL9566848 | 0.81 | P4HTM (0.55) | KDM4EP4HTMSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL9566817 | 0.80 | TRPV1 (0.55) | KDM4EP4HTMSMN1; SMN2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |