Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566867 | 0.90 | LMNA (0.57) | LMNASTAT3SMN1; SMN2P4HTMNR1H4 | |
| SCHEMBL9566892 | 0.89 | PLK1 (0.53) | LMNASTAT3SMN1; SMN2P4HTMNR1H4 | |
| SCHEMBL9566825 | 0.89 | P4HTM (0.66) | LMNASMN1; SMN2P4HTMMAPTHSD17B10 | |
| SCHEMBL9566884 | 0.88 | SMN1; SMN2 (0.55) | LMNASTAT3SMN1; SMN2P4HTMNR1H4 | |
| SCHEMBL9566790 | 0.88 | LMNA (0.59) | LMNASTAT3SMN1; SMN2P4HTMNR1H4 | |
| SCHEMBL9566821 | 0.85 | NR1H4 (0.54) | LMNASTAT3SMN1; SMN2P4HTMNR1H4 | |
| SCHEMBL9566817 | 0.84 | TRPV1 (0.55) | SMN1; SMN2P4HTMHPGDKDM4EALDH1A1 | |
| SCHEMBL9566787 | 0.83 | P4HTM (0.53) | LMNASMN1; SMN2P4HTMMAPTKDM4E | |
| SCHEMBL9566866 | 0.82 | KDM4E (0.56) | LMNASTAT3SMN1; SMN2P4HTMMAPT | |
| SCHEMBL9566740 | 0.82 | CXCR2 (0.54) | LMNASTAT3SMN1; SMN2P4HTMFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |