Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566818 | 0.82 | ALDH1A1 (0.44) | LNPEP | |
| SCHEMBL9566743 | 0.78 | ALDH1A1 (0.44) | LNPEP | |
| Hydrochloric Acid SCHEMBL9566744 | 0.77 | ALDH1A1 (0.43) | SMN1; SMN2LMNALNPEP | |
| SCHEMBL9566834 | 0.76 | LOXL2 (0.41) | — | |
| SCHEMBL9566730 | 0.75 | KDM4E (0.45) | LMNALNPEP | |
| SCHEMBL9566858 | 0.74 | HPGD (0.43) | SMN1; SMN2 | |
| SCHEMBL9566774 | 0.74 | SMN1; SMN2 (0.39) | SMN1; SMN2 | |
| SCHEMBL9566886 | 0.72 | MEN1 (0.41) | SMN1; SMN2LMNA | |
| SCHEMBL9566810 | 0.71 | LOXL2 (0.41) | SMN1; SMN2 | |
| SCHEMBL9706016 | 0.71 | ALDH1A1 (0.43) | SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |