Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 5/20 | 0.41 |
| ▸ | LOX | P28300 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566818 | 0.92 | ALDH1A1 (0.44) | HPGD | |
| SCHEMBL9566810 | 0.90 | LOXL2 (0.41) | LOXL2LOXHPGDOPRM1CYP1A2 | |
| SCHEMBL9566774 | 0.87 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL9566784 | 0.86 | LMNA (0.44) | LOXL2LOXCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9566858 | 0.85 | HPGD (0.43) | LOXL2LOXHPGDCYP1A2CYP2C9 | |
| SCHEMBL9354128 | 0.84 | LOXL2 (0.48) | LOXL2LOXHPGDOPRM1CYP1A2 | |
| SCHEMBL9566886 | 0.82 | MEN1 (0.41) | CYP1A2 | |
| SCHEMBL9566743 | 0.82 | ALDH1A1 (0.44) | HPGD | |
| Hydrochloric Acid SCHEMBL9566744 | 0.81 | ALDH1A1 (0.43) | HPGD | |
| SCHEMBL9706023 | 0.81 | LOXL2 (0.46) | LOXL2LOXHPGDOPRM1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |