Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566834 | 0.92 | LOXL2 (0.41) | HPGD | |
| SCHEMBL9566743 | 0.90 | ALDH1A1 (0.44) | ALDH1A1KDM4EHTTKDM4CL3MBTL1 | |
| SCHEMBL9566774 | 0.90 | SMN1; SMN2 (0.39) | — | |
| Hydrochloric Acid SCHEMBL9566744 | 0.89 | ALDH1A1 (0.43) | ALDH1A1KDM4EHTTKDM4CL3MBTL1 | |
| SCHEMBL9566730 | 0.87 | KDM4E (0.45) | ALDH1A1KDM4EHTTKDM4CL3MBTL1 | |
| SCHEMBL9566878 | 0.82 | EPHX2 (0.47) | LNPEP | |
| SCHEMBL9566810 | 0.82 | LOXL2 (0.41) | HPGD | |
| SCHEMBL9706016 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4EHTTKDM4CL3MBTL1 | |
| SCHEMBL9706010 | 0.81 | HPGD (0.44) | ALDH1A1KDM4EHTTKDM4CL3MBTL1 | |
| SCHEMBL9566858 | 0.81 | HPGD (0.43) | L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |