Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566941 | 0.89 | KIF11 (0.42) | PDE3BPDE3APARP1KDM4EALDH1A1 | |
| SCHEMBL9309057 | 0.82 | PARP1 (0.48) | PARP1KDM4EHTTDHODHALDH1A1 | |
| SCHEMBL9566894 | 0.79 | KIF11 (0.43) | PARP1KDM4EHTTALDH1A1TSHR | |
| SCHEMBL9308464 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1TSHRMAPTHIF1A | |
| SCHEMBL27387940 | 0.77 | MEN1 (0.46) | PARP1KDM4EALDH1A1KIF11 | |
| SCHEMBL27532886 | 0.76 | KIF11 (0.50) | PDE3BPDE3APARP1KDM4EHTT | |
| SCHEMBL27410853 | 0.76 | MAPT (0.44) | PDE3BPDE3APARP1KDM4EHTT | |
| SCHEMBL27409224 | 0.75 | KIF11 (0.44) | PDE3BPDE3AKDM4EHTTALDH1A1 | |
| SCHEMBL27410225 | 0.75 | DAO (0.49) | PARP1KDM4EHTTALDH1A1TSHR | |
| SCHEMBL27388577 | 0.74 | PTGS2 (0.53) | KDM4EHTTALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561252-A1 | 2-Oxoquinoline derivatives as angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1993-09-22 | — | — | EP | disclosed |