Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DDO | Q99489 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566941 | 0.81 | KIF11 (0.42) | KIF11RAB9APTGESCYP2C9HSD17B10 | |
| SCHEMBL9566907 | 0.80 | AR (0.41) | KIF11RAB9AARPTGESCYP2C9 | |
| SCHEMBL9566925 | 0.79 | PDE3B (0.45) | KIF11RAB9ACYP2C9TSHRMAPT | |
| SCHEMBL27532886 | 0.79 | KIF11 (0.50) | KIF11RAB9APTGESCYP2C9HSD17B10 | |
| SCHEMBL27410225 | 0.75 | DAO (0.49) | KIF11RAB9APTGESCYP2C9HSD17B10 | |
| SCHEMBL9308787 | 0.74 | PARP1 (0.48) | KIF11RAB9AHSD17B10TSHRMAPT | |
| SCHEMBL27413780 | 0.73 | KIF11 (0.46) | KIF11RAB9AARPTGESCYP2C9 | |
| SCHEMBL27409224 | 0.73 | KIF11 (0.44) | KIF11RAB9APTGESCYP2C9HSD17B10 | |
| SCHEMBL9311173 | 0.72 | PARP1 (0.45) | KIF11RAB9AMAPTDAOGAA | |
| SCHEMBL27420343 | 0.72 | KDM4E (0.46) | KIF11RAB9APTGESCYP2C9HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561252-A1 | 2-Oxoquinoline derivatives as angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1993-09-22 | — | — | EP | disclosed |