Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669914 | 0.84 | HCAR3 (0.50) | MAPTALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL4227750 | 0.79 | ALDH1A1 (0.56) | MAPTALDH1A1GAASMN1; SMN2MEN1 | |
| SCHEMBL28952779 | 0.79 | MAPT (0.50) | MAPTALDH1A1GAAHPGDHTT | |
| SCHEMBL111190 | 0.79 | MAPT (0.50) | MAPTALDH1A1GAAHPGDHTT | |
| SCHEMBL10385970 | 0.78 | MAPT (0.59) | MAPTALDH1A1GAAHPGDHTT | |
| SCHEMBL6269072 | 0.78 | MAPT (0.58) | MAPTALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL2470791 | 0.77 | HTR6 (0.59) | MAPTALDH1A1GAAHPGDHTT | |
| SCHEMBL6151067 | 0.76 | MAPT (0.50) | MAPTALDH1A1GAAHPGDHTT | |
| SCHEMBL20129837 | 0.75 | HTR6 (0.60) | MAPTALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL6151375 | 0.75 | MAPT (0.49) | MAPTALDH1A1GAAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547414-A2 | Process for the preparation of N-substituted nitro-p-phenylenediamines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-23 | — | — | EP | disclosed |