Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 11/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567019 | 0.99 | CFTR (0.35) | CTSBTDP1SMN1; SMN2NOTUMCFTR | |
| SCHEMBL9567016 | 0.96 | CTSB (0.36) | CTSBTDP1SMN1; SMN2NOTUMCRHR1 | |
| SCHEMBL9168174 | 0.83 | TDP1 (0.40) | CTSBTDP1SMN1; SMN2NOTUMCRHR1 | |
| SCHEMBL9423041 | 0.83 | TDP1 (0.40) | CTSBTDP1SMN1; SMN2NOTUMP2RX7 | |
| SCHEMBL29576263 | 0.83 | TDP1 (0.40) | CTSBTDP1SMN1; SMN2NOTUMCRHR1 | |
| SCHEMBL1807362 | 0.83 | TDP1 (0.52) | CTSBTDP1NOTUMMEN1KMT2A | |
| SCHEMBL6465173 | 0.82 | LMNA (0.47) | CTSBTDP1NOTUMP2RX7MEN1 | |
| Ethylene SCHEMBL9423310 | 0.81 | TDP1 (0.39) | CTSBTDP1NOTUMP2RX7MEN1 | |
| SCHEMBL8993584 | 0.81 | MEN1 (0.37) | CRHR1MEN1KMT2A | |
| SCHEMBL9423187 | 0.81 | TDP1 (0.38) | CTSBTDP1NOTUMCRHR1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542685-A1 | 3-Aryluracile derivatives and their use against weeds | CIBA-GEIGY AG (CH) | 1993-05-19 | — | — | EP | claimed |
| EP-0542685-A1 | 3-Aryluracile derivatives and their use against weeds | CIBA-GEIGY AG (CH) | 1993-05-19 | — | — | EP | disclosed |