Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993507 | 0.90 | GABRA1 (0.37) | MEN1KMT2ACRHR1HTR4GABRA1 | |
| SCHEMBL6699195 | 0.88 | CYP4F2 (0.44) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL6908332 | 0.86 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1NPSR1THRB | |
| SCHEMBL6697536 | 0.84 | MEN1 (0.44) | MEN1KMT2AALDH1A1NPSR1LMNA | |
| SCHEMBL9520570 | 0.83 | GAA (0.37) | HTR4GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7953670 | 0.83 | KMT2A (0.37) | MEN1KMT2ACRHR1ALDH1A1NPSR1 | |
| SCHEMBL9567016 | 0.83 | CTSB (0.36) | MEN1KMT2ACRHR1 | |
| SCHEMBL44446 | 0.82 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1NPSR1LMNA | |
| SCHEMBL4897613 | 0.82 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1NPSR1LMNA | |
| SCHEMBL29576263 | 0.81 | TDP1 (0.40) | MEN1KMT2ACRHR1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527764-A | 3-arylthionouracils useful as herbicides, defoliants, and desiccants | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1996-06-18 | — | — | US | disclosed |