Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | NRP1 | O14786 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567386 | 0.85 | DHODH (0.37) | ADORA1DHODHNRP1TRPA1SCN5A | |
| SCHEMBL9840555 | 0.84 | ADORA1 (0.40) | ADORA1DHODHNRP1TRPA1SCN5A | |
| SCHEMBL9567337 | 0.83 | KIF11 (0.41) | ADORA1DHODHPDE10AMAPTKDM4E | |
| SCHEMBL9567335 | 0.79 | ALDH1A1 (0.42) | IDO1MAPTKDM4EGLAMEN1 | |
| SCHEMBL9389298 | 0.79 | KDM4E (0.34) | ADORA1DHODHPDE2APDE4BPDE10A | |
| SCHEMBL1180132 | 0.74 | ALDH1A1 (0.48) | IDO1MAPTKDM4EGLAMEN1 | |
| SCHEMBL10591906 | 0.73 | DHODH (0.40) | ADORA1DHODHNRP1TRPA1SCN5A | |
| SCHEMBL9389588 | 0.72 | KDM4E (0.36) | DHODHPDE10AMAOAMAOBMAPT | |
| SCHEMBL10591159 | 0.72 | ADORA1 (0.39) | ADORA1DHODHNRP1TRPA1SCN5A | |
| SCHEMBL9567399 | 0.72 | ALDH1A1 (0.41) | IDO1MAPTKDM4EGLAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530147-A1 | 3-Cyano-2-phenyl-pyrroles as pesticides | CIBA-GEIGY AG (CH) | 1993-03-03 | — | — | EP | claimed |
| EP-0530147-A1 | 3-Cyano-2-phenyl-pyrroles as pesticides | CIBA-GEIGY AG (CH) | 1993-03-03 | — | — | EP | disclosed |