Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | NRP1 | O14786 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10333139 | 0.84 | ADORA1 (0.47) | ADORA1DHODHKDM5ADYRK1AKCNH2 | |
| SCHEMBL9567377 | 0.84 | ADORA1 (0.37) | ADORA1DHODHKDM5ANRP1TRPA1 | |
| SCHEMBL1180416 | 0.81 | KIF11 (0.46) | ADORA1DHODHDYRK1AKCNH2MAPT | |
| SCHEMBL10591199 | 0.79 | PTGS2 (0.46) | ADORA1DYRK1AIDO1MAPTMEN1 | |
| SCHEMBL8070637 | 0.78 | DYRK1A (0.44) | DYRK1AIDO1MAPTMEN1ALDH1A1 | |
| SCHEMBL10591906 | 0.77 | DHODH (0.40) | ADORA1DHODHKDM5ANRP1TRPA1 | |
| SCHEMBL10590224 | 0.77 | DYRK1A (0.43) | DHODHDYRK1APDE10AMAOAMAOB | |
| SCHEMBL10591159 | 0.76 | ADORA1 (0.39) | ADORA1DHODHKDM5ANRP1TRPA1 | |
| SCHEMBL9518992 | 0.75 | DYRK1A (0.42) | ADORA1DHODHDYRK1APDE10AMAOA | |
| SCHEMBL9389298 | 0.75 | KDM4E (0.34) | ADORA1DHODHDYRK1APDE2APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010098-A | Arylpyrrole insecticidal acaricidal and nematicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1991-04-23 | — | — | US | disclosed |
| US-4929634-A | ARYLPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0312723-A2 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |