SCHEMBL9567804

SCHEMBL9567804

Cc1ccccc1C=CC(=O)c1cccnc1

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.70
ALDH1A1 P00352 3/20 0.70
LMNA P02545 2/20 0.70
KMT2A Q03164 2/20 0.70
HPGD P15428 1/20 0.70
CYP1A1 P04798 8/20 0.69
CYP1A2 P05177 8/20 0.69
CYP1B1 Q16678 8/20 0.69
CYP3A4 P08684 6/20 0.69
CYP2D6 P10635 6/20 0.69
CAPN1 P07384 1/20 0.59
CTSL P07711 1/20 0.59
CTSB P07858 1/20 0.59
KDM4E B2RXH2 1/20 0.58
PKM P14618 1/20 0.58
MEN1 O00255 1/20 0.56
APP P05067 1/20 0.53
GSK3B P49841 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3597959 0.84 MAPT (0.72) MAPTALDH1A1LMNAKMT2AHPGD
SCHEMBL3597965 0.84 MAPT (0.72) MAPTALDH1A1LMNAKMT2AHPGD
SCHEMBL6936134 0.83 CYP1A1 (0.67) MAPTALDH1A1LMNAKMT2AHPGD
SCHEMBL351853 0.82 RAB9A (0.63) MAPTALDH1A1LMNAKMT2AHPGD
SCHEMBL1225684 0.82 RAB9A (0.63) MAPTALDH1A1LMNAKMT2AHPGD
SCHEMBL7660164 0.82 RAB9A (0.63) MAPTALDH1A1LMNAKMT2AHPGD
SCHEMBL31398692 0.82 RAB9A (0.63) MAPTALDH1A1LMNAKMT2AHPGD
SCHEMBL196923 0.82 MAPT (1.00) MAPTALDH1A1LMNAKMT2AHPGD
SCHEMBL196922 0.82 MAPT (1.00) MAPTALDH1A1LMNAKMT2AHPGD
SCHEMBL17233282 0.82 CYP1A2 (1.00) MAPTALDH1A1LMNAKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0570992-A1 Powder coatings NIPPON PAINT CO., LTD. (JP) 1993-11-24 EP disclosed
US-5034432-A Thermosetting or thermoplastic resins for powder coatings NIPPON PAINT CO., LTD. (JP) 1991-07-23 US disclosed
EP-0389080-A1 Powder coatings NIPPON PAINT CO., LTD. (JP) 1990-09-26 EP disclosed