Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | PTGIR | P43119 | 2/20 | 0.43 |
| ▸ | PREP | P48147 | 4/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | UGCG | Q16739 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568020 | 0.88 | MEN1 (0.48) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9048602 | 0.81 | PTGIR (0.71) | PTGIR | |
| SCHEMBL9427048 | 0.80 | PTGIR (0.52) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9568036 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9568059 | 0.77 | P2RX7 (0.46) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8713442 | 0.76 | MTNR1A (0.52) | PREPMTNR1AMTNR1BDGAT1UGCG | |
| SCHEMBL7304447 | 0.76 | DGAT1 (0.58) | ALDH1A1PREPMTNR1AMTNR1BDGAT1 | |
| SCHEMBL3406500 | 0.76 | DGAT1 (0.58) | ALDH1A1PREPMTNR1AMTNR1BDGAT1 | |
| SCHEMBL7292707 | 0.76 | DGAT1 (0.58) | ALDH1A1PREPMTNR1AMTNR1BDGAT1 | |
| SCHEMBL30612421 | 0.76 | DGAT1 (0.58) | ALDH1A1PREPMTNR1AMTNR1BDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |