Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3611898 | 0.81 | PLAU (0.46) | PLAUMTNR1BMTNR1AOPRD1DPP8 | |
| SCHEMBL8858441 | 0.80 | PTGIR (0.58) | — | |
| SCHEMBL9568005 | 0.76 | TRPM8 (0.39) | TDP1PLAUMTNR1BMTNR1AANPEP | |
| SCHEMBL18984385 | 0.71 | MTNR1A (0.44) | PLAUMTNR1BMTNR1AOPRD1DPP8 | |
| SCHEMBL18984178 | 0.71 | MTNR1A (0.45) | MTNR1BMTNR1AOPRD1DPP8DPP4 | |
| SCHEMBL16594081 | 0.71 | PLAU (0.52) | PLAUMTNR1BMTNR1AANPEP | |
| SCHEMBL11472821 | 0.70 | MTNR1A (0.45) | PLAUMTNR1BMTNR1AANPEP | |
| Hydrochloric Acid SCHEMBL7706015 | 0.69 | MTNR1A (0.40) | MTNR1BMTNR1AANPEPGRM7 | |
| SCHEMBL18984177 | 0.69 | MTNR1A (0.40) | PLAUMTNR1BMTNR1AOPRD1DPP8 | |
| SCHEMBL9567973 | 0.69 | HPGD (0.53) | MTNR1BMTNR1AGRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |