Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 3/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | NPY1R | P25929 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | TPH1 | P17752 | 1/20 | 0.41 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046845 | 0.83 | HPGD (0.47) | HPGDCYP3A4CYP2D6CYP2C9PKM | |
| SCHEMBL9046851 | 0.80 | PTGIR (0.48) | HPGDCYP3A4CYP2D6CYP2C9PKM | |
| SCHEMBL9568007 | 0.77 | CNR1 (0.50) | MTNR1AMTNR1B | |
| SCHEMBL9568071 | 0.75 | SLC6A4 (0.50) | HPGDMTNR1AMTNR1B | |
| SCHEMBL12422869 | 0.75 | ADRA1D (0.58) | MTNR1AMTNR1BNPY1RNPY5RADRA1D | |
| SCHEMBL9568016 | 0.74 | TACR1 (0.44) | MTNR1AMTNR1BTACR1 | |
| SCHEMBL30444843 | 0.74 | NAMPT (0.46) | MTNR1AMTNR1BNPY1RNPY5RADRA1D | |
| SCHEMBL2833768 | 0.74 | EPHX1 (0.47) | CYP2D6CYP2C19MTNR1AMTNR1BNPY1R | |
| SCHEMBL9567978 | 0.73 | ALDH1A1 (0.46) | HPGDMTNR1AMTNR1B | |
| SCHEMBL9688829 | 0.72 | DRD2 (0.63) | PKMMTNR1AMTNR1BNPY1RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |