Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047644 | 0.85 | PTGIR (0.36) | MAPK1NPC1RAB9AALDH1A1POLB | |
| SCHEMBL9568088 | 0.85 | OPRM1 (0.40) | MCHR1GHSRHTR1ASIGMAR1TSHR | |
| SCHEMBL8858485 | 0.83 | PTGIR (0.57) | — | |
| SCHEMBL9568175 | 0.80 | OPRM1 (0.39) | GHSRHTR1ASIGMAR1TSHRCYP19A1 | |
| SCHEMBL9568016 | 0.75 | TACR1 (0.44) | MCHR1USP30 | |
| SCHEMBL9050455 | 0.72 | DRD2 (0.39) | TSHR | |
| SCHEMBL11243114 | 0.71 | TSHR (0.53) | NPC1RAB9AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9050993 | 0.70 | PTGIR (0.39) | MCHR1 | |
| SCHEMBL1950916 | 0.69 | MCHR1 (0.50) | MCHR1HTR1ASIGMAR1CYP19A1 | |
| SCHEMBL2840174 | 0.69 | MEN1 (0.50) | SIGMAR1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |