Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568088 | 0.91 | OPRM1 (0.40) | OPRM1HTR1AGHSRSIGMAR1TSPO | |
| SCHEMBL9046065 | 0.86 | DRD2 (0.38) | OPRM1DRD2TSHR | |
| SCHEMBL9567995 | 0.80 | MCHR1 (0.40) | HTR1AGHSRSIGMAR1TSHRCYP19A1 | |
| SCHEMBL9050455 | 0.78 | DRD2 (0.39) | OPRM1DRD2TSHR | |
| SCHEMBL9047709 | 0.71 | PTGIR (0.57) | — | |
| SCHEMBL9047707 | 0.71 | PTGIR (0.41) | DRD2 | |
| SCHEMBL9047644 | 0.67 | PTGIR (0.36) | DRD2TSHR | |
| SCHEMBL9139949 | 0.67 | HTR1A (0.53) | OPRM1HTR1ASIGMAR1CYP19A1MTNR1A | |
| SCHEMBL13688297 | 0.66 | HTR1A (0.54) | OPRM1HTR1AGHSRDRD2OPRD1 | |
| SCHEMBL2840174 | 0.65 | MEN1 (0.50) | SIGMAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |